Publications

CIOMS-ICLAS International Guiding Principles for Biomedical Research Involving Animals

The 1985 International Guiding Principles for Biomedical Research Involving Animals have been revised by an ad hoc committee appointed by the Council for International Organizations for Medical Science (CIOMS) and the International Council for Laboratory Animal Science (ICLAS).

The revised International Guiding Principles for Biomedical Research Involving Animals reflect current best practices and standards of care in laboratory animal medicine and science and provide a touchstone or framework of responsibility and oversight to ensure the appropriate use of animals. They also may serve as a benchmark for advancing international collaboration in biomedical sciences.

It is hoped that international organizations and governmental agencies will adopt these revised International Guiding Principles for Biomedical Research Involving Animals and that they will encourage use by the scientific community worldwide.

The CIOMS principles may be translated into languages other than English, but any translation must include the following notice:
“Disclaimer: ICLAS does not guarantee the accuracy of this translation.”

Download the Principles

Other publications

Turner PV, Pekow C, Clark JM, Vergara P, Bayne K, White WJ, Kurosawa TM, Seok SH, Baneux P. Roles of the International Council for Laboratory Animal Science (ICLAS) and International Association of Colleges of Laboratory Animal Medicine (IACLAM) in the Global Organization and Support of 3Rs Advances in Laboratory Animal Science. J Am Assoc Lab Anim Sci. 2015 Mar;54(2):174-80. Get a pdf HERE.

Rose M, Everitt J, Hedrich H, Schofield J, Dennis M, Scott E, Griffin G; ICLAS Working Group on Harmonization: international guidance concerning the production care and use of genetically-altered animals. Lab Anim. 2013 Jul;47(3):142-52. Get a pdf HERE.

Fahey JR, Katoh H, Malcolm R, Perez AV. The case for genetic monitoring of mice and rats used in biomedical research. Mamm Genome. 2013 Apr;24(3-4):89-94.

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