HARRP (Harmonized Animal Research Reporting Principles)
Recently published — Harmonized Animal Research Reporting Principles (HARRP), the first step of a unified approach by ICLAS to improve research reporting standards worldwide. Osborne N, Avey MT, Anestidou L, Ritskes-Hoitinga M & Griffin G EMBO reports (2018) 19, e46069.
Now available as an open access article in EMBO reports: http://dx.doi.org/10.15252/embr.201846069
The HARRP principles are intended to improve the quality of animal based research, through encouraging complete and accurate reporting of animal based studies.
ICLAS’s intention is not to replace the excellent reporting guidelines already in existence. Rather, the intention is to improve the quality of animal-based research worldwide by providing a set of principles that can be easily translated into other languages. The HARRP can then be used as a minimum standard achievably globally, and upon which more technical guidance can be built.
The ICLAS working group charged with harmonizing reporting principles used the three main sets of reporting standards available at the start of the exercise as a basis (the Gold Standard Publication Checklist, the ARRIVE guidelines; and ILAR’s Guidance on the Description of Animal Research in Scientific Publications). The structured analysis of these guidelines, subsequent development of the principles and their review is further described in Osborne et al (2018).
 Members of the working group were representatives of groups with current reporting guidelines and/or experts in research reporting.
|BOX 1–Animal Research Reporting Principles
7. Housing, Husbandry and Research Environment: Housing, husbandry and all other non-experimental research environmental factors related to animal-based research must be reported.
8. Data Availability: All animal-derived in vitro or ex vivo data data must be made available.
Hooijmans CR, Leenaars M, Ritskes-Hoitinga M. (2010) A gold standard publication checklist to improve the quality of animal studies, to fully integrate the three Rs, and to make systematic reviews more feasible. Altern Lab Anim 38(2): 167–182. Available: http://www.atla.org.uk/a-gold-standard-publication-checklist-to-improve-the-quality-of-animal-studies-to-fully-integrate-the-three-rs-and-to-make-systematic-reviews-more-feasible/.
Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG. (2013) Improving bioscience research reporting: The arrive guidelines for reporting animal research. Animals 4(1): 35–44. doi:10.3390/ani4010035.17. Available: http://www.mdpi.com/2076-2615/4/1/35.
National Research Council. (2011) Guidance for the Description of Animal Research in Scientific Publications. Washington, DC: National Academies Press. Available: https://www.nap.edu/catalog/13241/guidance-for-the-description-of-animal-research-in-scientific-publications.
Harmonization of guidelines on genetically altered animals
- Revision of the CIOMS 1985 International Guiding Principles for Biomedical Research Involving Animals.
- Harmonization of guidelines on euthanasia (2006)
- Harmonization of guidelines on endpoints (2006)
- Harmonization of guidance on the ethical review of proposals for the use of animals (2010)
- Harmonization of guidance on the education and training of animal users in science (2010)